Gene Expression Databases


Gene expression databases store information about the absolute or relative abundance of gene transcription products in various biological samples, such as cells from a particular tissue in a particular organism, or a particular cell line. These databases allow one to access, select, retrieve and combine for analysis gene expression datasets generated by one's own or other laboratories.

Keywords: gene expression; microarrays; database

Figure 1.

Conceptual design of microarray‐based gene expression database ArrayExpress.



Brazma A, Hingamp P, Quackenbush J et al. (2001) Minimum information about a microarray experiment (MIAME)–toward standards for microarray data. Nature Genetics 29: 365–371.

Brazma A, Robinson A, Cameron G and Ashburner M (2000) One‐stop shop for microarray data. Nature 403: 699–700.

Lockhart JD, Dong H, Byrne MC et al. (1996) Expression monitoring by hybridization to high‐density oligonucleotide arrays. Nature Biotechnology 14: 1675–1680.

Rayner TF, Rocca‐Serra P, Spellman PT et al. (2006) A simple spreadsheet‐based, MIAME‐supportive format for microarray data: MAGE‐TAB. BMC Bioinformatics 7: 489.

Schena M, Shalon D, Davis RW and Brown PO (1995) Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 270: 467–470.

Spellman PT, Miller M, Stewart J et al. (2002) Design and implementation of microarray gene expression markup language (MAGE‐ML). Genome Biology 3(9): research 0046.1–0046.9.

Velculescu VE, Zhang L, Vogelstein B and Kinzler KW (1995) Serial analysis of gene expression. Science 270: 484–487.

Further Reading

The chipping forecast II (2002) Nature Genetics (suppl. 4) , vol 32.

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Brazma, Alvis, and Sarkans, Ugis(Dec 2007) Gene Expression Databases. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1002/9780470015902.a0005248.pub2]