Chromosome 14


Human chromosome 14 is an acrocentric chromosome, rich in satellites on the short arm, which contains some 3.4% of the genetic material in the genome. It is characterized by several gene clusters including rRNA, T‐cell receptor, and immunoglobulin heavy chain genes, plus several regions containing imprinted genes.

Keywords: immunoglobulin; T‐cell receptor; protease inhibitor; imprinting, lymphoma


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Further Reading

Arden B, Clark SP, Kabelitz D and Mak TW (1995) Human T‐cell receptor variable gene segment families. Immunogenetics 42: 455–500.

Bruls T, Gyapay G, Petit JL, et al. (2001) A physical map of human chromosome 14. Nature 409: 947–948.

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Oakey RJ and Beechey CV (2002) Imprinted genes: identification by chromosome rearrangements and post‐genomic strategies. Trends in Genetics 18: 359–366.

Web Links

Celera. Human Genomic sequence database

Ensembl Genome Browser. Annotated human genomic sequence database

Genome Database. Comprehensive human database of genome features

Marshfield Center for Medical Genetics. Human comprehensive genetic map database

Mitelman Database of Chromosome Aberrations in Cancer. Comprehensive list of chromosome aberrations associated with cancer

NCBI homepage. Comprehensive sequence database with annotation

Online Mendelian Inheritance in Man (OMIM). Comprehensive database of diseases and genes

UCSC Genome Bioinformatics. Annotated human genomic sequence database

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How to Cite close
Kamnasaran, Deepak, and Cox, Diane W(Jan 2006) Chromosome 14. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1038/npg.els.0005823]